FEEDING-FASTING CYCLE
• The utilization of metabolic fuel is not the same during the 24 hour period because humans are intermittent feeders.
• The fed (postprandial) state occurs during and just after a meal. • Plasma substrate levels are elevated above the fasting level.
• The fasting (postabsorptive) state occurs several hours (usually 10 - 12 hours) after eating.
• The metabolic fuels used by tissues are derived from mobilized stores of fuel molecules.
HMP shunt
• Starvation occurs after extended fasting (2 to 3 days without food).
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